Gene description for Hnrnpa3
Gene name heterogeneous nuclear ribonucleoprotein A3
Gene symbol Hnrnpa3
Other names/aliases Hnrpa3
Species Rattus norvegicus
 Database cross references - Hnrnpa3
ExoCarta ExoCarta_362152
Vesiclepedia VP_362152
Entrez Gene 362152
UniProt Q6URK4  
 Hnrnpa3 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Hnrnpa3
Molecular Function
    RNA binding GO:0003723 IEA
    mRNA binding GO:0003729 IMP
    mRNA 3'-UTR binding GO:0003730 IBA
    RNA transmembrane transporter activity GO:0051033 IMP
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA transport GO:0051028 IMP
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    postsynaptic density GO:0014069 EXP
    postsynaptic density GO:0014069 IDA
    postsynaptic density GO:0014069 IMP
    ribonucleoprotein granule GO:0035770 IDA
    catalytic step 2 spliceosome GO:0071013 IBA
    catalytic step 2 spliceosome GO:0071013 ISO
    postsynapse GO:0098794 EXP
    postsynapse GO:0098794 IDA
    postsynapse GO:0098794 IMP
    glutamatergic synapse GO:0098978 EXP
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
    ribonucleoprotein complex GO:1990904 IDA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified Hnrnpa3 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Hnrnpa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Snca  
Affinity Capture-MS Rattus norvegicus
2 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Hnrnpa3 is involved
No pathways found





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