Gene description for Hnrnpa3
Gene name heterogeneous nuclear ribonucleoprotein A3
Gene symbol Hnrnpa3
Other names/aliases Hnrpa3
Species Rattus norvegicus
 Database cross references - Hnrnpa3
ExoCarta ExoCarta_362152
Entrez Gene 362152
UniProt Q6URK4  
 Hnrnpa3 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Hnrnpa3
Molecular Function
    mRNA binding GO:0003729 IMP
    poly(A) RNA binding GO:0044822 ISO
    RNA transmembrane transporter activity GO:0051033 IMP
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    mRNA transport GO:0051028 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    neuron projection GO:0043005 IDA
    nucleus GO:0005634 ISO
    spliceosomal complex GO:0005681 IEA
    catalytic step 2 spliceosome GO:0071013 ISO
    ribonucleoprotein granule GO:0035770 IDA
 Experiment description of studies that identified Hnrnpa3 in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Hnrnpa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpa3 is involved
No pathways found





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