Gene description for Vopp1
Gene name vesicular, overexpressed in cancer, prosurvival protein 1
Gene symbol Vopp1
Other names/aliases Ecop
RGD1306494
Species Rattus norvegicus
 Database cross references - Vopp1
ExoCarta ExoCarta_362374
Entrez Gene 362374
UniProt B5DEK8  
 Vopp1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Vopp1
Molecular Function
    signal transducer activity GO:0004871 ISO
Biological Process
    signal transduction GO:0007165 ISO
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    integral component of organelle membrane GO:0031301 ISO
    endosome GO:0005768 ISO
    cytoplasmic vesicle membrane GO:0030659 ISO
 Experiment description of studies that identified Vopp1 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Vopp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vopp1 is involved
No pathways found





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