Gene description for Suclg2
Gene name succinate-CoA ligase, GDP-forming, beta subunit
Gene symbol Suclg2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Suclg2
ExoCarta ExoCarta_362404
Vesiclepedia VP_362404
Entrez Gene 362404
 Suclg2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Suclg2
Molecular Function
    magnesium ion binding GO:0000287 IEA
    succinate-CoA ligase (ADP-forming) activity GO:0004775 IBA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IBA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IDA
    ATP binding GO:0005524 IEA
    GTP binding GO:0005525 IEA
    GDP binding GO:0019003 IDA
    protein-containing complex binding GO:0044877 IDA
Biological Process
    tricarboxylic acid cycle GO:0006099 IBA
    tricarboxylic acid cycle GO:0006099 IDA
    tricarboxylic acid cycle GO:0006099 IEA
    succinyl-CoA metabolic process GO:0006104 IBA
    succinyl-CoA metabolic process GO:0006104 IDA
    succinate metabolic process GO:0006105 IDA
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    protein-containing complex GO:0032991 IDA
    succinate-CoA ligase complex GO:0042709 IBA
    succinate-CoA ligase complex (GDP-forming) GO:0045244 IDA
    succinate-CoA ligase complex (GDP-forming) GO:0045244 ISO
 Experiment description of studies that identified Suclg2 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Suclg2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Suclg2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here