Gene description for Lpcat3
Gene name lysophosphatidylcholine acyltransferase 3
Gene symbol Lpcat3
Other names/aliases Grcc3f
Mboat5
Oact5
Species Rattus norvegicus
 Database cross references - Lpcat3
ExoCarta ExoCarta_362434
Entrez Gene 362434
UniProt Q5FVN0  
 Lpcat3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lpcat3
Molecular Function
    1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 ISO
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    phospholipid biosynthetic process GO:0008654 IEA
    regulation of plasma lipoprotein particle levels GO:0097006 ISO
Subcellular Localization
    membrane GO:0016020 ISO
    integral component of membrane GO:0016021 IEA
    cellular_component GO:0005575 ND
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Lpcat3 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lpcat3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lpcat3 is involved
PathwayEvidenceSource
Acyl chain remodelling of PC IEA Reactome
Acyl chain remodelling of PE IEA Reactome
Acyl chain remodelling of PS IEA Reactome





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