Gene description for Gpn2
Gene name GPN-loop GTPase 2
Gene symbol Gpn2
Other names/aliases Atpbd1b
RGD1311749
Species Rattus norvegicus
 Database cross references - Gpn2
ExoCarta ExoCarta_362614
Vesiclepedia VP_362614
Entrez Gene 362614
UniProt D4A7C0  
 Gpn2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gpn2
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 IEA
Biological Process
    biological_process GO:0008150 ND
 Experiment description of studies that identified Gpn2 in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gpn2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gpn2 is involved
No pathways found





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