Gene description for Rpl11
Gene name ribosomal protein L11
Gene symbol Rpl11
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rpl11
ExoCarta ExoCarta_362631
Entrez Gene 362631
UniProt P62914  
 Rpl11 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Rpl11
Molecular Function
    structural constituent of ribosome GO:0003735 IEA
    rRNA binding GO:0019843 IEA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    translation GO:0006412 IEA
    protein targeting GO:0006605 ISO
    protein localization to nucleus GO:0034504 ISS
    rRNA processing GO:0006364 ISO
    ribosomal large subunit biogenesis GO:0042273 ISO
Subcellular Localization
    cytosolic large ribosomal subunit GO:0022625 ISO
    cytoplasm GO:0005737 ISO
    extracellular exosome GO:0070062 ISO
    nucleolus GO:0005730 ISS
    ribosome GO:0005840 IEA
    membrane GO:0016020 ISO
 Experiment description of studies that identified Rpl11 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rpl11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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