Gene description for Tmx1
Gene name thioredoxin-related transmembrane protein 1
Gene symbol Tmx1
Other names/aliases Txndc1
Species Rattus norvegicus
 Database cross references - Tmx1
ExoCarta ExoCarta_362751
Entrez Gene 362751
 Tmx1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Tmx1
Molecular Function
    disulfide oxidoreductase activity GO:0015036 ISO
    protein disulfide isomerase activity GO:0003756 IBA
Biological Process
    protein folding GO:0006457 IBA
    oxidation-reduction process GO:0055114 IEA
    cell redox homeostasis GO:0045454 IEA
    response to endoplasmic reticulum stress GO:0034976 ISO
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 ISO
    endoplasmic reticulum GO:0005783 ISO
    nucleolus GO:0005730 ISO
 Experiment description of studies that identified Tmx1 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Tmx1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmx1 is involved
No pathways found





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