Gene description for Slc44a2
Gene name solute carrier family 44 (choline transporter), member 2
Gene symbol Slc44a2
Other names/aliases RGD1309680
Species Rattus norvegicus
 Database cross references - Slc44a2
ExoCarta ExoCarta_363024
Entrez Gene 363024
UniProt B4F795  
 Slc44a2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc44a2
Molecular Function
    signal transducer activity GO:0004871 ISO
Biological Process
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO
    signal transduction GO:0007165 ISO
    transport GO:0006810 IEA
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    extracellular exosome GO:0070062 ISO
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Slc44a2 in exosomes
1
Experiment ID 97
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc44a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here