Gene description for Gpd1l
Gene name glycerol-3-phosphate dehydrogenase 1-like
Gene symbol Gpd1l
Other names/aliases RGD1560123
Species Rattus norvegicus
 Database cross references - Gpd1l
ExoCarta ExoCarta_363159
Entrez Gene 363159
 Gpd1l identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Gpd1l
Molecular Function
    ion channel binding GO:0044325 ISO
    glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367 IEA
    sodium channel regulator activity GO:0017080 ISO
    molecular_function GO:0003674 ND
    NAD binding GO:0051287 IEA
    protein homodimerization activity GO:0042803 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    negative regulation of protein kinase C signaling GO:0090038 ISO
    NAD metabolic process GO:0019674 ISO
    biological_process GO:0008150 ND
    NADH metabolic process GO:0006734 ISO
    glycerol-3-phosphate catabolic process GO:0046168 IEA
    positive regulation of sodium ion transport GO:0010765 ISO
    oxidation-reduction process GO:0055114 IEA
    negative regulation of peptidyl-serine phosphorylation GO:0033137 ISO
    regulation of sodium ion transmembrane transporter activity GO:2000649 ISO
    positive regulation of protein localization to cell surface GO:2000010 ISO
    regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 ISO
    ventricular cardiac muscle cell action potential GO:0086005 ISO
    regulation of heart rate GO:0002027 ISO
Subcellular Localization
    glycerol-3-phosphate dehydrogenase complex GO:0009331 IEA
    plasma membrane GO:0005886 ISO
    cellular_component GO:0005575 ND
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Gpd1l in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Gpd1l
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gpd1l is involved
No pathways found





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