Gene description for Obsl1
Gene name obscurin-like 1
Gene symbol Obsl1
Other names/aliases RGD1306073
Species Rattus norvegicus
 Database cross references - Obsl1
ExoCarta ExoCarta_363259
Vesiclepedia VP_363259
Entrez Gene 363259
UniProt D3ZZ80  
 Obsl1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Obsl1
Biological Process
    microtubule cytoskeleton organization GO:0000226 ISO
    microtubule cytoskeleton organization GO:0000226 ISS
    Golgi organization GO:0007030 IMP
    Golgi organization GO:0007030 ISO
    regulation of mitotic nuclear division GO:0007088 ISO
    regulation of mitotic nuclear division GO:0007088 ISS
    protein localization to Golgi apparatus GO:0034067 ISO
    positive regulation of dendrite morphogenesis GO:0050775 IMP
    positive regulation of dendrite morphogenesis GO:0050775 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    Golgi apparatus GO:0005794 ISO
    Golgi apparatus GO:0005794 ISS
    centrosome GO:0005813 ISO
    centrosome GO:0005813 ISS
    perinuclear region of cytoplasm GO:0048471 ISO
    perinuclear region of cytoplasm GO:0048471 ISS
    3M complex GO:1990393 ISO
    3M complex GO:1990393 ISS
 Experiment description of studies that identified Obsl1 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Obsl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Obsl1 is involved
No pathways found





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