Gene description for Taz
Gene name tafazzin
Gene symbol Taz
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Taz
ExoCarta ExoCarta_363521
Entrez Gene 363521
 Taz identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Taz
Molecular Function
    1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 ISO
    molecular_function GO:0003674 ND
    O-acyltransferase activity GO:0008374 IBA
Biological Process
    hemopoiesis GO:0030097 ISO
    cardiolipin acyl-chain remodeling GO:0035965 IBA
    cristae formation GO:0042407 ISO
    cardiac muscle tissue development GO:0048738 ISO
    skeletal muscle tissue development GO:0007519 ISO
    mitochondrial ATP synthesis coupled electron transport GO:0042775 ISO
    mitochondrial respiratory chain complex I assembly GO:0032981 ISO
    muscle contraction GO:0006936 ISO
    cardiolipin biosynthetic process GO:0032049 ISO
    inner mitochondrial membrane organization GO:0007007 IBA
    biological_process GO:0008150 ND
    heart development GO:0007507 ISO
    cardiac muscle contraction GO:0060048 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 ISO
    mitochondrial membrane GO:0031966 IBA
    membrane GO:0016020 ISO
    intrinsic component of membrane GO:0031224 IBA
    mitochondrion GO:0005739 ISO
    cellular_component GO:0005575 ND
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Taz in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Taz
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Taz is involved
No pathways found





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