Gene description for Rras2
Gene name related RAS viral (r-ras) oncogene homolog 2
Gene symbol Rras2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rras2
ExoCarta ExoCarta_365355
Entrez Gene 365355
 Rras2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Reticulocytes 21828046    
 Gene ontology annotations for Rras2
Molecular Function
    GTP binding GO:0005525 IEA
    molecular_function GO:0003674 ND
Biological Process
    regulation of neuron death GO:1901214 ISO
    cellular process GO:0009987 ISO
    osteoblast differentiation GO:0001649 ISO
    biological_process GO:0008150 ND
    positive regulation of cell migration GO:0030335 ISO
    Ras protein signal transduction GO:0007265 ISO
Subcellular Localization
    intracellular GO:0005622 ISO
    focal adhesion GO:0005925 ISO
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 ISO
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Rras2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rras2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rras2 is involved
No pathways found





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