Gene description for Rras2
Gene name related RAS viral (r-ras) oncogene homolog 2
Gene symbol Rras2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rras2
ExoCarta ExoCarta_365355
Vesiclepedia VP_365355
Entrez Gene 365355
 Rras2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Reticulocytes 21828046    
 Gene ontology annotations for Rras2
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 ISO
    GTP binding GO:0005525 IBA
    GDP binding GO:0019003 IBA
Biological Process
    Ras protein signal transduction GO:0007265 ISO
    Ras protein signal transduction GO:0007265 ISO
    biological_process GO:0008150 ND
    cell migration GO:0016477 ISO
    Schwann cell migration GO:0036135 ISO
    positive regulation of Schwann cell migration GO:1900149 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    endomembrane system GO:0012505 IEA
 Experiment description of studies that identified Rras2 in exosomes
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rras2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNF207  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Rras2 is involved
No pathways found





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