Gene description for Zasp52
Gene name Z band alternatively spliced PDZ-motif protein 52
Gene symbol Zasp52
Other names/aliases CG12968
CG12969
CG30084
CG8242
DmelCG30084
Z(210)
ZASP52
Zasp
Zbp210
dzasp
tun
tungus
zasp
zasp52
Species Drosophila melanogaster
 Database cross references - Zasp52
ExoCarta ExoCarta_36740
Entrez Gene 36740
UniProt A1ZA47  
 Zasp52 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Zasp52
Molecular Function
    muscle alpha-actinin binding GO:0051371 IPI
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
Biological Process
    muscle structure development GO:0061061 IMP
    myofibril assembly GO:0030239 IMP
Subcellular Localization
    cell leading edge GO:0031252 IDA
    focal adhesion GO:0005925 IDA
    stress fiber GO:0001725 IDA
    zonula adherens GO:0005915 IDA
    basolateral plasma membrane GO:0016323 IDA
    basal part of cell GO:0045178 IDA
    Z disc GO:0030018 IDA
    apical part of cell GO:0045177 IDA
    muscle tendon junction GO:0005927 IDA
 Experiment description of studies that identified Zasp52 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Zasp52
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zasp52 is involved
No pathways found





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