Gene description for cora
Gene name coracle
Gene symbol cora
Other names/aliases CG11949
COR
Cor
Cora
Coracle
D4.1
DmelCG11949
cor
l(2)k08713
Species Drosophila melanogaster
 Database cross references - cora
ExoCarta ExoCarta_37205
Entrez Gene 37205
UniProt Q9V8R9  
 cora identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for cora
Molecular Function
    cytoskeletal protein binding GO:0008092 ISS
    actin binding GO:0003779 IEA
    structural molecule activity GO:0005198 IEA
Biological Process
    regulation of tube size, open tracheal system GO:0035151 IMP
    dorsal closure GO:0007391 TAS
    cell adhesion involved in heart morphogenesis GO:0061343 IMP
    heart process GO:0003015 IMP
    establishment or maintenance of cell polarity GO:0007163 NAS
    adult somatic muscle development GO:0007527 IMP
    septate junction assembly GO:0019991 TAS
    embryonic morphogenesis GO:0048598 IMP
    cell-cell junction organization GO:0045216 TAS
    maintenance of imaginal disc-derived wing hair orientation GO:0035321 IMP
    establishment of glial blood-brain barrier GO:0060857 IMP
    cytoskeleton organization GO:0007010 ISS
    chitin-based embryonic cuticle biosynthetic process GO:0008362 TAS
    protein targeting to membrane GO:0006612 TAS
    salivary gland morphogenesis GO:0007435 TAS
Subcellular Localization
    plasma membrane GO:0005886 IDA
    septate junction GO:0005918 TAS
    fusome GO:0045169 IDA
    smooth septate junction GO:0005920 IDA
    spectrosome GO:0045170 IDA
    cytoskeleton GO:0005856 ISS
 Experiment description of studies that identified cora in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for cora
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which cora is involved
No pathways found





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