Gene description for betaTub60D
Gene name beta-Tubulin at 60D
Gene symbol betaTub60D
Other names/aliases 143391_i_at
3t
B3t
BETA 60D
CG3401
D.m.BETA-60D
DTB3
Dmbeta3
DmelCG3401
T
Tub
Tub60D
beta-Tub60D
beta-Tub6D
beta-tub
beta3
beta3 TU
beta3-Tub
beta3-tubulin
beta3TUB
beta3Tub
beta3t
beta60C
betaTub
betaTub3
betaTub60C
beta[[3]] tubulin
beta[[3]]-Tub
beta[[3]]-tubulin
betatub60D
p50
p50/tubulin
p53
p53/tubulin
Species Drosophila melanogaster
 Database cross references - betaTub60D
ExoCarta ExoCarta_37888
Vesiclepedia VP_37888
Entrez Gene 37888
UniProt P08841  
 betaTub60D identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for betaTub60D
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IDA
Biological Process
    axonogenesis GO:0007409 IMP
    axon guidance GO:0007411 IMP
    response to light stimulus GO:0009416 IMP
    larval behavior GO:0030537 IMP
Subcellular Localization
    cytoplasm GO:0005737 HDA
    microtubule GO:0005874 IDA
 Experiment description of studies that identified betaTub60D in sEVs
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for betaTub60D
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tab2  
Affinity Capture-MS Drosophila melanogaster
2 PGRP-LE  
Affinity Capture-MS Drosophila melanogaster
3 Tak1  
Affinity Capture-MS Drosophila melanogaster
4 key  
Affinity Capture-MS Drosophila melanogaster
5 CG15676  
Two-hybrid Drosophila melanogaster
6 cry  
Proximity Label-MS Drosophila melanogaster
7 Dref  
Affinity Capture-MS Drosophila melanogaster
8 me31B  
Proximity Label-MS Drosophila melanogaster
9 CG15450  
Two-hybrid Drosophila melanogaster
10 l(2)37Ce  
Two-hybrid Drosophila melanogaster
11 Fadd  
Affinity Capture-MS Drosophila melanogaster
12 CG14894  
Proximity Label-MS Drosophila melanogaster
13 Iap2  
Affinity Capture-MS Drosophila melanogaster
14 Trf2  
Affinity Capture-MS Drosophila melanogaster
15 ird5  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml



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