Gene description for Nurf-38
Gene name Nucleosome remodeling factor - 38kD
Gene symbol Nurf-38
Other names/aliases 38
CG4634
DmelCG4634
N38
NURF
NURF 38
NURF-38
NURF38
Nurf 38
Nurf38
dNURF
l(2)k16102
p38
p38/NURF-38
Species Drosophila melanogaster
 Database cross references - Nurf-38
ExoCarta ExoCarta_37922
Vesiclepedia VP_37922
Entrez Gene 37922
UniProt O77460  
 Nurf-38 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Nurf-38
Molecular Function
    inorganic diphosphate phosphatase activity GO:0004427 IDA
Biological Process
    chromatin remodeling GO:0006338 IDA
    nucleosome organization GO:0034728 IDA
    regulation of hemocyte proliferation GO:0035206 IMP
    positive regulation of DNA-templated transcription GO:0045893 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IGI
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    NURF complex GO:0016589 IDA
    NURF complex GO:0016589 IPI
    NURF complex GO:0016589 TAS
 Experiment description of studies that identified Nurf-38 in sEVs
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Nurf-38
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Bap60  
Two-hybrid Drosophila melanogaster
2 Caf1  
Affinity Capture-Western Drosophila melanogaster
3 Fkbp14  
Affinity Capture-MS Drosophila melanogaster
4 Hn  
Two-hybrid Drosophila melanogaster
5 CG6843  
Two-hybrid Drosophila melanogaster
6 Dref  
Affinity Capture-MS Drosophila melanogaster
7 CG5991  
Two-hybrid Drosophila melanogaster
8 Ef1alpha48D  
Two-hybrid Drosophila melanogaster
9 CG11164  
Two-hybrid Drosophila melanogaster
10 E(bx)  
Co-fractionation Drosophila melanogaster
Reconstituted Complex Drosophila melanogaster
Reconstituted Complex Drosophila melanogaster
11 zuc  
Proximity Label-MS Drosophila melanogaster
12 scramb2  
Two-hybrid Drosophila melanogaster
13 Tom20  
Proximity Label-MS Drosophila melanogaster
14 CG1847  
Two-hybrid Drosophila melanogaster
15 Iswi  
Affinity Capture-Western Drosophila melanogaster
16 dom  
Two-hybrid Drosophila melanogaster
17 Snm1  
Two-hybrid Drosophila melanogaster
18 EcR  
Protein-peptide Drosophila melanogaster
19 Trf2  
Affinity Capture-MS Drosophila melanogaster
20 CG2046  
Two-hybrid Drosophila melanogaster
21 CG12470  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here