Gene description for Ap5b1
Gene name adaptor-related protein complex 5, beta 1 subunit
Gene symbol Ap5b1
Other names/aliases Gm962
Species Mus musculus
 Database cross references - Ap5b1
ExoCarta ExoCarta_381201
Entrez Gene 381201
UniProt Q3TAP4  
 Ap5b1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ap5b1
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
    endosomal transport GO:0016197 ISO
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    AP-type membrane coat adaptor complex GO:0030119 ISO
 Experiment description of studies that identified Ap5b1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ap5b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ap5b1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here