Gene description for Mup20
Gene name major urinary protein 20
Gene symbol Mup20
Other names/aliases Gm12560
Mup24
OTTMUSG00000007485
darcin
Species Mus musculus
 Database cross references - Mup20
ExoCarta ExoCarta_381530
Vesiclepedia VP_381530
Entrez Gene 381530
UniProt Q5FW60  
 Mup20 identified in sEVs derived from the following tissue/cell type
Faeces 33431899    
Faeces 33431899    
 Gene ontology annotations for Mup20
Molecular Function
    mating pheromone activity GO:0000772 IDA
    odorant binding GO:0005549 IBA
    pheromone binding GO:0005550 IDA
    small molecule binding GO:0036094 IEA
Biological Process
    signal transduction GO:0007165 IEA
    olfactory learning GO:0008355 IDA
    olfactory learning GO:0008355 IDA
    positive regulation of neurogenesis GO:0050769 IDA
    vocalization behavior GO:0071625 IDA
    positive regulation of neural precursor cell proliferation GO:2000179 IDA
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Mup20 in sEVs
1
Experiment ID 303
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
2
Experiment ID 304
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
 Protein-protein interactions for Mup20
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mup20 is involved
No pathways found





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