Gene description for Eid2
Gene name EP300 interacting inhibitor of differentiation 2
Gene symbol Eid2
Other names/aliases Cri2
Species Mus musculus
 Database cross references - Eid2
ExoCarta ExoCarta_386655
Entrez Gene 386655
UniProt Q6X7S9  
 Eid2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Eid2
Molecular Function
    SMAD binding GO:0046332 ISO
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    cell differentiation GO:0030154 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO
    regulation of cell proliferation GO:0042127 ISO
    transcription, DNA-templated GO:0006351 IEA
    multicellular organismal development GO:0007275 IEA
    regulation of transforming growth factor beta receptor signaling pathway GO:0017015 ISO
    transforming growth factor beta receptor complex assembly GO:0007181 ISO
    SMAD protein complex assembly GO:0007183 ISO
    negative regulation of transcription, DNA-templated GO:0045892 ISO
    muscle organ development GO:0007517 IEA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Eid2 in exosomes
Experiment ID 15
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for Eid2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eid2 is involved
No pathways found

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