Gene description for OR51B6
Gene name olfactory receptor, family 51, subfamily B, member 6
Gene symbol OR51B6
Other names/aliases HOR5'Beta6
Species Homo sapiens
 Database cross references - OR51B6
ExoCarta ExoCarta_390058
Entrez Gene 390058
HGNC 19600
UniProt Q9H340  
 OR51B6 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for OR51B6
Molecular Function
    G-protein coupled receptor activity GO:0004930 IEA
    olfactory receptor activity GO:0004984 NAS
Biological Process
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 NAS
    G-protein coupled receptor signaling pathway GO:0007186 IEA
    sensory perception of smell GO:0007608 NAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    integral component of membrane GO:0016021 NAS
 Experiment description of studies that identified OR51B6 in exosomes
1
Experiment ID 237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for OR51B6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OR51B6 is involved
PathwayEvidenceSource
Olfactory Signaling Pathway TAS Reactome





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