Gene description for Pcdha2
Gene name protocadherin alpha 2
Gene symbol Pcdha2
Other names/aliases rCNRv02
Species Rattus norvegicus
 Database cross references - Pcdha2
ExoCarta ExoCarta_393086
Vesiclepedia VP_393086
Entrez Gene 393086
 Pcdha2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Pcdha2
Molecular Function
    calcium ion binding GO:0005509 IEA
Biological Process
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    endoplasmic reticulum GO:0005783 ISO
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Pcdha2 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Pcdha2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pcdha2 is involved
No pathways found





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