Gene description for ARHGAP6
Gene name	Rho GTPase activating protein 6
Gene symbol	ARHGAP6
Other names/aliases	RHOGAP6 RHOGAPX-1
Species	Homo sapiens
Database cross references - ARHGAP6
ExoCarta	ExoCarta_395
Entrez Gene	395
HGNC	676
MIM	300118
UniProt	O43182
ARHGAP6 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for ARHGAP6

Molecular Function     GTPase activator activity GO:0005096 IEA     phospholipase activator activity GO:0016004 IDA     phospholipase binding GO:0043274 IPI     SH3/SH2 adaptor activity GO:0005070 TAS     SH3 domain binding GO:0017124 IEA Biological Process     positive regulation of signal transduction GO:0009967 TAS     small GTPase mediated signal transduction GO:0007264 TAS     actin filament polymerization GO:0030041 NAS     activation of phospholipase C activity GO:0007202 IDA     positive regulation of GTPase activity GO:0043547 IEA     Rho protein signal transduction GO:0007266 NAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     negative regulation of stress fiber assembly GO:0051497 IMP     negative regulation of focal adhesion assembly GO:0051895 IMP     focal adhesion assembly GO:0048041 IEA     positive regulation of phospholipase activity GO:0010518 IDA Subcellular Localization     cytoplasm GO:0005737 IMP     actin cytoskeleton GO:0015629 ISS     cytosol GO:0005829 TAS     actin filament GO:0005884 NAS