Gene description for Aats-tyr
Gene name Tyrosyl-tRNA synthetase
Gene symbol Aats-tyr
Other names/aliases CG4561
DmelCG4561
TyrRS
YARS
YRS
anon-EST:Posey261
dTyrRS
dYARS
Species Drosophila melanogaster
 Database cross references - Aats-tyr
ExoCarta ExoCarta_39829
Vesiclepedia VP_39829
Entrez Gene 39829
 Aats-tyr identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Aats-tyr
Molecular Function
    tyrosine-tRNA ligase activity GO:0004831 IDA
    tyrosine-tRNA ligase activity GO:0004831 TAS
Biological Process
    tyrosyl-tRNA aminoacylation GO:0006437 TAS
Subcellular Localization
    cytoplasm GO:0005737 TAS
 Experiment description of studies that identified Aats-tyr in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aats-tyr
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 eIF-4B  
Affinity Capture-MS Drosophila melanogaster
2 Zasp66  
Two-hybrid Drosophila melanogaster
3 RpL19  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Aats-tyr is involved
No pathways found





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