Gene description for Vkorc1l1
Gene name vitamin K epoxide reductase complex, subunit 1-like 1
Gene symbol Vkorc1l1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Vkorc1l1
ExoCarta ExoCarta_399684
Vesiclepedia VP_399684
Entrez Gene 399684
UniProt Q6TEK3  
 Vkorc1l1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Vkorc1l1
Molecular Function
    nucleotide binding GO:0000166 IEA
    vitamin-K-epoxide reductase (warfarin-sensitive) activity GO:0047057 IBA
    vitamin-K-epoxide reductase (warfarin-sensitive) activity GO:0047057 IDA
    vitamin-K-epoxide reductase (warfarin-sensitive) activity GO:0047057 IEA
    vitamin-K-epoxide reductase (warfarin-sensitive) activity GO:0047057 ISO
    quinone binding GO:0048038 IEA
Biological Process
    transcription initiation at RNA polymerase III promoter GO:0006384 IEA
    peptidyl-glutamic acid carboxylation GO:0017187 ISO
    peptidyl-glutamic acid carboxylation GO:0017187 ISS
    cellular response to oxidative stress GO:0034599 ISO
    cellular response to oxidative stress GO:0034599 ISS
    vitamin K metabolic process GO:0042373 IBA
    vitamin K metabolic process GO:0042373 IDA
    vitamin K metabolic process GO:0042373 IEA
    vitamin K metabolic process GO:0042373 ISO
Subcellular Localization
    RNA polymerase III complex GO:0005666 IEA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    endoplasmic reticulum membrane GO:0005789 ISO
    endoplasmic reticulum membrane GO:0005789 ISS
 Experiment description of studies that identified Vkorc1l1 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Vkorc1l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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