Gene description for FAM174B
Gene name family with sequence similarity 174, member B
Gene symbol FAM174B
Other names/aliases -
Species Homo sapiens
 Database cross references - FAM174B
ExoCarta ExoCarta_400451
Vesiclepedia VP_400451
Entrez Gene 400451
HGNC 34339
UniProt Q3ZCQ3  
 FAM174B identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for FAM174B
Biological Process
    Golgi organization GO:0007030 IMP
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified FAM174B in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for FAM174B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FAM174B is involved
No pathways found





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