Gene description for CANX
Gene name calnexin
Gene symbol CANX
Other names/aliases PP90
Species Canis lupus familiaris
 Database cross references - CANX
ExoCarta ExoCarta_403908
Vesiclepedia VP_403908
Entrez Gene 403908
UniProt -   
 CANX identified in sEVs derived from the following tissue/cell type
Kidney cells 33638284    
Kidney cells 33638284    
 Gene ontology annotations for CANX
Molecular Function
    calcium ion binding GO:0005509 IEA
    unfolded protein binding GO:0051082 IEA
Biological Process
    protein folding GO:0006457 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified CANX in sEVs
1
Experiment ID 393
MISEV standards
EM
Biophysical techniques
CD63|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33638284    
Organism Canis lupus familiaris
Experiment description "Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition"
Authors "Shafiq A, Suwakulsiri W, Rai A, Chen M, Greening DW, Zhu HJ, Xu R, Simpson RJ."
Journal name Proteomics
Publication year 2021
Sample Kidney cells
Sample name MDCK - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
2
Experiment ID 394
MISEV standards
EM
Biophysical techniques
CD63|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 33638284    
Organism Canis lupus familiaris
Experiment description "Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition"
Authors "Shafiq A, Suwakulsiri W, Rai A, Chen M, Greening DW, Zhu HJ, Xu R, Simpson RJ."
Journal name Proteomics
Publication year 2021
Sample Kidney cells
Sample name MDCK (21D1) - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
 Protein-protein interactions for CANX
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CANX is involved
No pathways found





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