Gene description for CLDN3
Gene name claudin 3
Gene symbol CLDN3
Other names/aliases -
Species Bos taurus
 Database cross references - CLDN3
ExoCarta ExoCarta_404153
Entrez Gene 404153
UniProt Q765N9  
 CLDN3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CLDN3
Molecular Function
    structural molecule activity GO:0005198 IEA
    identical protein binding GO:0042802 IEA
Biological Process
    calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 IEA
    epithelial cell morphogenesis GO:0003382 ISS
    response to hypoxia GO:0001666 IEA
Subcellular Localization
    lateral plasma membrane GO:0016328 IEA
    extracellular exosome GO:0070062 IEA
    integral component of membrane GO:0016021 IEA
    bicellular tight junction GO:0005923 ISS
 Experiment description of studies that identified CLDN3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CLDN3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CLDN3 is involved
No pathways found





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