Gene description for CD63
Gene name CD63 molecule
Gene symbol CD63
Other names/aliases -
Species Bos taurus
 Database cross references - CD63
ExoCarta ExoCarta_404156
Entrez Gene 404156
UniProt Q9XSK2  
 CD63 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CD63
Biological Process
    cell migration GO:0016477 ISS
    positive regulation of integrin-mediated signaling pathway GO:2001046 ISS
    regulation of vascular endothelial growth factor signaling pathway GO:1900746 ISS
    cell-matrix adhesion GO:0007160 ISS
    positive regulation of receptor internalization GO:0002092 ISS
    protein transport GO:0015031 IEA
    pigment granule maturation GO:0048757 ISS
    endosome to melanosome transport GO:0035646 ISS
Subcellular Localization
    multivesicular body, internal vesicle GO:0097487 ISS
    melanosome GO:0042470 IEA
    lysosomal membrane GO:0005765 ISS
    late endosome membrane GO:0031902 ISS
    integral component of membrane GO:0016021 IEA
    intrinsic component of plasma membrane GO:0031226 ISS
 Experiment description of studies that identified CD63 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD63
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD63 is involved
PathwayEvidenceSource
Platelet degranulation IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here