Gene description for tacc
Gene name transforming acidic coiled-coil protein
Gene symbol tacc
Other names/aliases CG9765
D-TACC
D-tacc
DTACC
DmelCG9765
TACC
TACCdm
acc
d-tacc
dTACC
dtacc
Species Drosophila melanogaster
 Database cross references - tacc
ExoCarta ExoCarta_40589
Entrez Gene 40589
 tacc identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for tacc
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 TAS
Biological Process
    pronuclear migration GO:0035046 IMP
    female meiotic division GO:0007143 TAS
    microtubule cytoskeleton organization GO:0000226 IMP
    pole cell formation GO:0007279 IMP
    mitotic spindle organization GO:0007052 TAS
    protein localization GO:0008104 TAS
    mitotic nuclear division GO:0007067 NAS
    pronuclear fusion GO:0007344 TAS
    nuclear migration GO:0007097 IMP
    negative regulation of microtubule depolymerization GO:0007026 TAS
Subcellular Localization
    spindle pole GO:0000922 IDA
    pericentriolar material GO:0000242 NAS
    centrosome GO:0005813 TAS
    microtubule associated complex GO:0005875 IDA
    astral microtubule GO:0000235 TAS
    spindle microtubule GO:0005876 TAS
 Experiment description of studies that identified tacc in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for tacc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which tacc is involved
No pathways found





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