Gene description for Olr445
Gene name olfactory receptor 445
Gene symbol Olr445
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Olr445
ExoCarta ExoCarta_405936
Entrez Gene 405936
 Olr445 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Olr445
Molecular Function
    odorant binding GO:0005549 IBA
    olfactory receptor activity GO:0004984 IEA
    G-protein coupled receptor activity GO:0004930 IBA
Biological Process
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IEA
    sensory perception of smell GO:0007608 IBA
    G-protein coupled receptor signaling pathway GO:0007186 IEA
Subcellular Localization
    integral component of plasma membrane GO:0005887 IBA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Olr445 in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Olr445
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Olr445 is involved
No pathways found





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