Gene description for Krt2
Gene name keratin 2, type II
Gene symbol Krt2
Other names/aliases Kb2
Species Rattus norvegicus
 Database cross references - Krt2
ExoCarta ExoCarta_406228
Entrez Gene 406228
UniProt Q6IG02  
 Krt2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Krt2
Molecular Function
    molecular_function GO:0003674 ND
    structural molecule activity GO:0005198 IEA
Biological Process
    biological_process GO:0008150 ND
    hair follicle morphogenesis GO:0031069 IEA
    keratinization GO:0031424 ISO
    keratinocyte activation GO:0032980 ISO
    intermediate filament organization GO:0045109 IEA
    keratinocyte proliferation GO:0043616 ISO
    keratinocyte migration GO:0051546 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    extracellular space GO:0005615 ISO
    Golgi apparatus GO:0005794 ISO
    extracellular exosome GO:0070062 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    cellular_component GO:0005575 ND
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    keratin filament GO:0045095 IEA
 Experiment description of studies that identified Krt2 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Krt2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt2 is involved
No pathways found





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