Gene description for Krt2
Gene name keratin 2, type II
Gene symbol Krt2
Other names/aliases Kb2
Species Rattus norvegicus
 Database cross references - Krt2
ExoCarta ExoCarta_406228
Entrez Gene 406228
UniProt Q6IG02  
 Krt2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Krt2
Molecular Function
    molecular_function GO:0003674 ND
    structural molecule activity GO:0005198 IEA
Biological Process
    biological_process GO:0008150 ND
    hair follicle morphogenesis GO:0031069 IEA
    keratinization GO:0031424 ISO
    keratinocyte activation GO:0032980 ISO
    intermediate filament organization GO:0045109 IEA
    keratinocyte proliferation GO:0043616 ISO
    keratinocyte migration GO:0051546 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    extracellular space GO:0005615 ISO
    Golgi apparatus GO:0005794 ISO
    extracellular exosome GO:0070062 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    cellular_component GO:0005575 ND
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    keratin filament GO:0045095 IEA
 Experiment description of studies that identified Krt2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Krt2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt2 is involved
No pathways found





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