Gene description for KRIT1
Gene name KRIT1, ankyrin repeat containing
Gene symbol KRIT1
Other names/aliases CCM1
Species Bos taurus
 Database cross references - KRIT1
ExoCarta ExoCarta_407996
Vesiclepedia VP_407996
Entrez Gene 407996
UniProt Q6TNJ1  
 KRIT1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for KRIT1
Molecular Function
    protein binding GO:0005515 IEA
Biological Process
    negative regulation of angiogenesis GO:0016525 IEA
    cell redox homeostasis GO:0045454 IEA
    regulation of establishment of cell polarity GO:2000114 IEA
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified KRIT1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KRIT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KRIT1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here