Gene description for HSPA5
Gene name heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Gene symbol HSPA5
Other names/aliases grp78
Species Bos taurus
 Database cross references - HSPA5
ExoCarta ExoCarta_415113
Entrez Gene 415113
UniProt Q0VCX2  
 HSPA5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HSPA5
Molecular Function
    ATP binding GO:0005524 IEA
Biological Process
    maintenance of protein localization in endoplasmic reticulum GO:0035437 ISS
    positive regulation of cell migration GO:0030335 ISS
Subcellular Localization
    melanosome GO:0042470 IEA
    endoplasmic reticulum lumen GO:0005788 IEA
 Experiment description of studies that identified HSPA5 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSPA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HSPA5 is involved
No pathways found





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