Gene description for CG4390
Gene name CG4390 gene product from transcript CG4390-RB
Gene symbol CG4390
Other names/aliases DmelCG4390
Species Drosophila melanogaster
 Database cross references - CG4390
ExoCarta ExoCarta_42396
Vesiclepedia VP_42396
Entrez Gene 42396
 CG4390 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG4390
Molecular Function
    serine hydrolase activity GO:0017171 HDA
 Experiment description of studies that identified CG4390 in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG4390
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nplp2  
Affinity Capture-MS Drosophila melanogaster
2 Fer2LCH  
Affinity Capture-MS Drosophila melanogaster
3 Cpr64Ac  
Affinity Capture-MS Drosophila melanogaster
4 CG34205  
Affinity Capture-MS Drosophila melanogaster
5 Lsp2  
Affinity Capture-MS Drosophila melanogaster
6 Rfabg  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which CG4390 is involved
No pathways found





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