Gene description for SMIM22
Gene name small integral membrane protein 22
Gene symbol SMIM22
Other names/aliases -
Species Homo sapiens
 Database cross references - SMIM22
ExoCarta ExoCarta_440335
Vesiclepedia VP_440335
Entrez Gene 440335
HGNC 48329
UniProt K7EJ46  
 SMIM22 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SMIM22
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of cell migration GO:0030335 IMP
    regulation of actin cytoskeleton organization GO:0032956 IMP
    regulation of cell population proliferation GO:0042127 IBA
    regulation of cell population proliferation GO:0042127 IMP
    regulation of cell cycle GO:0051726 IMP
    lipid droplet formation GO:0140042 IMP
Subcellular Localization
    late endosome GO:0005770 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified SMIM22 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SMIM22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SMIM22 is involved
No pathways found





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