Gene description for LOC440786
Gene name uncharacterized LOC440786
Gene symbol LOC440786
Other names/aliases -
Species Homo sapiens
 Database cross references - LOC440786
ExoCarta ExoCarta_440786
Entrez Gene 440786
 LOC440786 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for LOC440786
Molecular Function
    antigen binding GO:0003823 NAS
Biological Process
    Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS
    immune response GO:0006955 NAS
    receptor-mediated endocytosis GO:0006898 TAS
    Fc-epsilon receptor signaling pathway GO:0038095 TAS
    complement activation, classical pathway GO:0006958 TAS
    regulation of immune response GO:0050776 TAS
    complement activation GO:0006956 TAS
    innate immune response GO:0045087 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    plasma membrane GO:0005886 TAS
    extracellular region GO:0005576 TAS
    blood microparticle GO:0072562 IDA
 Experiment description of studies that identified LOC440786 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for LOC440786
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LOC440786 is involved
No pathways found





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