Gene description for EIF5A
Gene name eukaryotic translation initiation factor 5A
Gene symbol EIF5A
Other names/aliases -
Species Bos taurus
 Database cross references - EIF5A
ExoCarta ExoCarta_444990
Entrez Gene 444990
UniProt Q6EWQ7  
 EIF5A identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF5A
Molecular Function
    ribosome binding GO:0043022 IEA
    translation elongation factor activity GO:0003746 IEA
Biological Process
    mRNA transport GO:0051028 IEA
    positive regulation of apoptotic process GO:0043065 IEA
    positive regulation of translational termination GO:0045905 IEA
    translational frameshifting GO:0006452 IEA
    positive regulation of translational elongation GO:0045901 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
    nuclear pore GO:0005643 IEA
 Experiment description of studies that identified EIF5A in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF5A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EIF5A is involved
PathwayEvidenceSource
Hypusine synthesis from eIF5A-lysine IEA Reactome





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