Gene description for EIF5A
Gene name eukaryotic translation initiation factor 5A
Gene symbol EIF5A
Other names/aliases -
Species Bos taurus
 Database cross references - EIF5A
ExoCarta ExoCarta_444990
Entrez Gene 444990
UniProt Q6EWQ7  
 EIF5A identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF5A
Molecular Function
    ribosome binding GO:0043022 IEA
    translation elongation factor activity GO:0003746 IEA
Biological Process
    mRNA transport GO:0051028 IEA
    positive regulation of apoptotic process GO:0043065 IEA
    positive regulation of translational termination GO:0045905 IEA
    translational frameshifting GO:0006452 IEA
    positive regulation of translational elongation GO:0045901 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
    nuclear pore GO:0005643 IEA
 Experiment description of studies that identified EIF5A in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF5A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EIF5A is involved
Hypusine synthesis from eIF5A-lysine IEA Reactome

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