Gene description for Aats-val
Gene name Valyl-tRNA synthetase
Gene symbol Aats-val
Other names/aliases BEST:LD45671
CG4062
DmelCG4062
VRS
ValRS
l(2)03531
l(2)rI255
ld45671
Species Drosophila melanogaster
 Database cross references - Aats-val
ExoCarta ExoCarta_45783
Vesiclepedia VP_45783
Entrez Gene 45783
 Aats-val identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Aats-val
Molecular Function
    valine-tRNA ligase activity GO:0004832 TAS
Biological Process
    valyl-tRNA aminoacylation GO:0006438 TAS
Subcellular Localization
    cytoplasm GO:0005737 TAS
 Experiment description of studies that identified Aats-val in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aats-val
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTPsyn  
Proximity Label-MS Drosophila melanogaster
2 Traf-like  
Two-hybrid Drosophila melanogaster
3 CG43691  
Two-hybrid Drosophila melanogaster
4 Prm  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Aats-val is involved
No pathways found





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