Gene description for bic
Gene name bicaudal
Gene symbol bic
Other names/aliases 107/12
5A
BcDNA.GM05329
BcDNA:GM05329
Bic
Btf
CG3644
DmelCG3644
E(2)Bic
E(Bic)
l(2)49Da
l(2)k10712
l(2)vr22
vr22
Species Drosophila melanogaster
 Database cross references - bic
ExoCarta ExoCarta_45827
Vesiclepedia VP_45827
Entrez Gene 45827
 bic identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for bic
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    embryonic development via the syncytial blastoderm GO:0001700 IMP
    regulation of pole plasm oskar mRNA localization GO:0007317 IMP
    pole plasm protein localization GO:0007318 IMP
    protein transport GO:0015031 TAS
    intracellular mRNA localization involved in anterior/posterior axis specification GO:0060811 IMP
    regulation of establishment of protein localization GO:0070201 IMP
Subcellular Localization
    nascent polypeptide-associated complex GO:0005854 ISS
 Experiment description of studies that identified bic in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for bic
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Arp10  
Two-hybrid Drosophila melanogaster
Two-hybrid Drosophila melanogaster
2 CTPsyn  
Proximity Label-MS Drosophila melanogaster
3 C1GalTA  
Two-hybrid Drosophila melanogaster
4 Nha2  
Two-hybrid Drosophila melanogaster
5 CG4415  
Two-hybrid Drosophila melanogaster
6 CG10510  
Two-hybrid Drosophila melanogaster
7 Sbp2  
Two-hybrid Drosophila melanogaster
8 CG42329  
Two-hybrid Drosophila melanogaster
9 HP1b  
Two-hybrid Drosophila melanogaster
10 CG5144  
Two-hybrid Drosophila melanogaster
11 cactin  
Two-hybrid Drosophila melanogaster
12 Lim3  
Two-hybrid Drosophila melanogaster
13 CG5168  
Two-hybrid Drosophila melanogaster
14 Nacalpha  
Two-hybrid Drosophila melanogaster
Two-hybrid Drosophila melanogaster
15 Pka-C3  
Two-hybrid Drosophila melanogaster
16 CSN4  
Two-hybrid Drosophila melanogaster
17 CG15136  
Two-hybrid Drosophila melanogaster
18 Poxm  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which bic is involved
No pathways found





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