Gene description for bic
Gene name bicaudal
Gene symbol bic
Other names/aliases 107/12
5A
BcDNA.GM05329
BcDNA:GM05329
Bic
Btf
CG3644
DmelCG3644
E(2)Bic
E(Bic)
l(2)49Da
l(2)k10712
l(2)vr22
vr22
Species Drosophila melanogaster
 Database cross references - bic
ExoCarta ExoCarta_45827
Entrez Gene 45827
 bic identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for bic
Biological Process
    regulation of pole plasm oskar mRNA localization GO:0007317 IMP
    regulation of establishment of protein localization GO:0070201 IMP
    intracellular mRNA localization involved in anterior/posterior axis specification GO:0060811 IMP
Subcellular Localization
    nascent polypeptide-associated complex GO:0005854 NAS
    microtubule associated complex GO:0005875 IDA
 Experiment description of studies that identified bic in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for bic
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which bic is involved
No pathways found





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