Gene description for TLR7
Gene name toll-like receptor 7
Gene symbol TLR7
Other names/aliases -
Species Bos taurus
 Database cross references - TLR7
ExoCarta ExoCarta_493686
Vesiclepedia VP_493686
Entrez Gene 493686
 TLR7 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TLR7
Molecular Function
    protein binding GO:0005515 IEA
    pattern recognition receptor activity GO:0038187 IEA
Biological Process
    toll-like receptor signaling pathway GO:0002224 IEA
    canonical NF-kappaB signal transduction GO:0007249 IEA
    positive regulation of interleukin-6 production GO:0032755 IEA
    toll-like receptor 7 signaling pathway GO:0034154 IEA
    defense response to virus GO:0051607 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified TLR7 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TLR7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TLR7 is involved
No pathways found





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