Gene description for TPM2
Gene name tropomyosin 2 (beta)
Gene symbol TPM2
Other names/aliases -
Species Bos taurus
 Database cross references - TPM2
ExoCarta ExoCarta_497015
Entrez Gene 497015
UniProt Q5KR48  
 TPM2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TPM2
Molecular Function
    actin binding GO:0003779 IEA
Biological Process
    regulation of ATPase activity GO:0043462 IEA
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified TPM2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TPM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TPM2 is involved
PathwayEvidenceSource
Smooth Muscle Contraction IEA Reactome
Striated Muscle Contraction IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here