Gene description for TPM3
Gene name tropomyosin 3
Gene symbol TPM3
Other names/aliases -
Species Bos taurus
 Database cross references - TPM3
ExoCarta ExoCarta_497019
Entrez Gene 497019
UniProt Q5KR47  
 TPM3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TPM3
Molecular Function
    actin binding GO:0003779 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
    stress fiber GO:0001725 IEA
 Experiment description of studies that identified TPM3 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TPM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TPM3 is involved
PathwayEvidenceSource
Smooth Muscle Contraction IEA Reactome
Striated Muscle Contraction IEA Reactome





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