Gene description for MTHFR
Gene name methylenetetrahydrofolate reductase (NAD(P)H)
Gene symbol MTHFR
Other names/aliases -
Species Bos taurus
 Database cross references - MTHFR
ExoCarta ExoCarta_497032
Entrez Gene 497032
UniProt Q5I598  
 MTHFR identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MTHFR
Molecular Function
    methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    methionine metabolic process GO:0006555 IEA
    tetrahydrofolate interconversion GO:0035999 IEA
 Experiment description of studies that identified MTHFR in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MTHFR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MTHFR is involved
No pathways found





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