Gene description for MTHFR
Gene name methylenetetrahydrofolate reductase (NAD(P)H)
Gene symbol MTHFR
Other names/aliases -
Species Bos taurus
 Database cross references - MTHFR
ExoCarta ExoCarta_497032
Vesiclepedia VP_497032
Entrez Gene 497032
UniProt Q5I598  
 MTHFR identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MTHFR
Molecular Function
    methylenetetrahydrofolate reductase (NAD(P)H) activity GO:0004489 IEA
    FAD binding GO:0071949 IEA
Biological Process
    methionine biosynthetic process GO:0009086 IEA
    tetrahydrofolate interconversion GO:0035999 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
 Experiment description of studies that identified MTHFR in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MTHFR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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