Gene description for Uqcrq
Gene name ubiquinol-cytochrome c reductase, complex III subunit VII
Gene symbol Uqcrq
Other names/aliases Qpc
Species Rattus norvegicus
 Database cross references - Uqcrq
ExoCarta ExoCarta_497902
Entrez Gene 497902
UniProt Q7TQ16  
 Uqcrq identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Uqcrq
Molecular Function
    ubiquinol-cytochrome-c reductase activity GO:0008121 IEA
Biological Process
    hypothalamus development GO:0021854 IEA
    subthalamus development GO:0021539 IEA
    hydrogen ion transmembrane transport GO:1902600 IEA
    midbrain development GO:0030901 IEA
    thalamus development GO:0021794 IEA
    pons development GO:0021548 IEA
    pyramidal neuron development GO:0021860 IEA
    cerebellar Purkinje cell layer development GO:0021680 IEA
    oxidation-reduction process GO:0055114 IEA
    hippocampus development GO:0021766 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    integral component of membrane GO:0016021 IEA
    respiratory chain GO:0070469 IEA
    mitochondrial inner membrane GO:0005743 ISO
 Experiment description of studies that identified Uqcrq in exosomes
1
Experiment ID 97
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Uqcrq
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Uqcrq is involved
PathwayEvidenceSource
Respiratory electron transport IEA Reactome





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