Gene description for Arl8a
Gene name ADP-ribosylation factor-like 8A
Gene symbol Arl8a
Other names/aliases RGD1565940
Species Rattus norvegicus
 Database cross references - Arl8a
ExoCarta ExoCarta_498234
Vesiclepedia VP_498234
Entrez Gene 498234
 Arl8a identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Arl8a
Molecular Function
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 ISO
Biological Process
    anterograde axonal transport GO:0008089 IBA
    anterograde axonal transport GO:0008089 ISO
    protein transport GO:0015031 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    lysosomal membrane GO:0005765 IBA
    midbody GO:0030496 ISO
    late endosome membrane GO:0031902 IEA
    spindle midzone GO:0051233 ISO
    axon cytoplasm GO:1904115 IEA
 Experiment description of studies that identified Arl8a in sEVs
1
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Arl8a
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Dao  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Arl8a is involved
No pathways found





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