Gene description for Fam114a1
Gene name family with sequence similarity 114, member A1
Gene symbol Fam114a1
Other names/aliases RGD1560201
Species Rattus norvegicus
 Database cross references - Fam114a1
ExoCarta ExoCarta_498366
Vesiclepedia VP_498366
Entrez Gene 498366
 Fam114a1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Fam114a1
Biological Process
    heart valve morphogenesis GO:0003179 ISO
    inflammatory response GO:0006954 ISO
    gene expression GO:0010467 ISO
    fibroblast migration GO:0010761 ISO
    angiotensin-activated signaling pathway GO:0038166 ISO
    fibroblast proliferation GO:0048144 ISO
    tissue remodeling GO:0048771 ISO
    fibroblast activation GO:0072537 ISO
    connective tissue replacement GO:0097709 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    Golgi apparatus GO:0005794 ISO
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Fam114a1 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Fam114a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STXBP5L  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Fam114a1 is involved
No pathways found





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