Gene description for Rab43
Gene name RAB43, member RAS oncogene family
Gene symbol Rab43
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rab43
ExoCarta ExoCarta_500249
Vesiclepedia VP_500249
Entrez Gene 500249
UniProt Q53B90  
 Rab43 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Rab43
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IEA
    GTPase activity GO:0003924 ISO
    GTPase activity GO:0003924 ISS
    GTP binding GO:0005525 IEA
Biological Process
    autophagosome assembly GO:0000045 IBA
    intracellular protein transport GO:0006886 IBA
    Golgi organization GO:0007030 ISO
    Golgi organization GO:0007030 ISS
    virion assembly GO:0019068 IEA
    retrograde transport, plasma membrane to Golgi GO:0035526 ISO
    retrograde transport, plasma membrane to Golgi GO:0035526 ISS
    cellular response to type II interferon GO:0071346 ISO
    phagosome maturation GO:0090382 ISO
    phagosome maturation GO:0090382 ISS
Subcellular Localization
    Golgi apparatus GO:0005794 ISO
    Golgi apparatus GO:0005794 ISS
    endomembrane system GO:0012505 IBA
    phagocytic vesicle membrane GO:0030670 IEA
    synaptic vesicle membrane GO:0030672 IEA
    phagocytic vesicle GO:0045335 ISO
    phagocytic vesicle GO:0045335 ISS
 Experiment description of studies that identified Rab43 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rab43
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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