Gene description for CLDN11
Gene name claudin 11
Gene symbol CLDN11
Other names/aliases OSP
OTM
Species Homo sapiens
 Database cross references - CLDN11
ExoCarta ExoCarta_5010
Vesiclepedia VP_5010
Entrez Gene 5010
HGNC 8514
MIM 601326
UniProt O75508  
 CLDN11 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CLDN11
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IMP
    identical protein binding GO:0042802 ISS
Biological Process
    cell adhesion GO:0007155 IBA
    spermatogenesis GO:0007283 IEA
    axon ensheathment GO:0008366 IEA
    calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 ISS
    bicellular tight junction assembly GO:0070830 IBA
    tight junction assembly GO:0120192 IDA
Subcellular Localization
    lipid droplet GO:0005811 IDA
    neurofilament GO:0005883 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    bicellular tight junction GO:0005923 IBA
    bicellular tight junction GO:0005923 ISS
    cell junction GO:0030054 IDA
    axon GO:0030424 IDA
    basal part of cell GO:0045178 IEA
    tight junction GO:0070160 IDA
 Experiment description of studies that identified CLDN11 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CLDN11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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