Gene description for Ppip5k2
Gene name diphosphoinositol pentakisphosphate kinase 2
Gene symbol Ppip5k2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ppip5k2
ExoCarta ExoCarta_501194
Vesiclepedia VP_501194
Entrez Gene 501194
 Ppip5k2 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Ppip5k2
Molecular Function
    inositol hexakisphosphate kinase activity GO:0000828 IBA
    inositol hexakisphosphate kinase activity GO:0000828 ISO
    diphosphoinositol pentakisphosphate kinase activity GO:0000829 IBA
    inositol hexakisphosphate 5-kinase activity GO:0000832 IEA
    ATP binding GO:0005524 ISO
    5-diphosphoinositol pentakisphosphate 1-kinase activity GO:0033857 IBA
    5-diphosphoinositol pentakisphosphate 1-kinase activity GO:0033857 ISO
    inositol hexakisphosphate 1-kinase activity GO:0052723 IEA
Biological Process
    inositol metabolic process GO:0006020 IBA
    inositol phosphate biosynthetic process GO:0032958 IBA
Subcellular Localization
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Ppip5k2 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Ppip5k2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ppip5k2 is involved
No pathways found





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