Gene description for Coro1c
Gene name coronin, actin binding protein 1C
Gene symbol Coro1c
Other names/aliases RGD1564490
Species Rattus norvegicus
 Database cross references - Coro1c
ExoCarta ExoCarta_501841
Entrez Gene 501841
 Coro1c identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Coro1c
Molecular Function
    Rac GTPase binding GO:0048365 ISO
    actin filament binding GO:0051015 ISO
Biological Process
    negative regulation of epithelial cell migration GO:0010633 ISO
    regulation of substrate adhesion-dependent cell spreading GO:1900024 ISO
    positive regulation of lamellipodium morphogenesis GO:2000394 ISO
    regulation of protein phosphorylation GO:0001932 ISO
    regulation of fibroblast migration GO:0010762 ISO
    negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 ISO
    negative regulation of substrate adhesion-dependent cell spreading GO:1900025 ISO
    regulation of ruffle assembly GO:1900027 ISO
    negative regulation of protein phosphorylation GO:0001933 ISO
    negative regulation of focal adhesion assembly GO:0051895 ISO
    neural crest cell migration GO:0001755 ISO
    regulation of epithelial cell migration GO:0010632 ISO
    activation of GTPase activity GO:0090630 ISO
    establishment of protein localization GO:0045184 ISO
    actin cytoskeleton organization GO:0030036 IBA
    regulation of focal adhesion assembly GO:0051893 ISO
Subcellular Localization
    flotillin complex GO:0016600 ISO
    focal adhesion GO:0005925 ISO
    cytoskeleton GO:0005856 ISO
    actin cytoskeleton GO:0015629 ISO
    lateral plasma membrane GO:0016328 ISO
    vesicle GO:0031982 ISO
    lamellipodium GO:0030027 ISO
 Experiment description of studies that identified Coro1c in exosomes
Experiment ID 225
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Coro1c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Coro1c is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here