Gene description for Coro1c
Gene name coronin, actin binding protein 1C
Gene symbol Coro1c
Other names/aliases RGD1564490
Species Rattus norvegicus
 Database cross references - Coro1c
ExoCarta ExoCarta_501841
Entrez Gene 501841
 Coro1c identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Coro1c
Molecular Function
    Rac GTPase binding GO:0048365 ISO
    actin filament binding GO:0051015 ISO
Biological Process
    negative regulation of epithelial cell migration GO:0010633 ISO
    regulation of substrate adhesion-dependent cell spreading GO:1900024 ISO
    positive regulation of lamellipodium morphogenesis GO:2000394 ISO
    regulation of protein phosphorylation GO:0001932 ISO
    regulation of fibroblast migration GO:0010762 ISO
    negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 ISO
    negative regulation of substrate adhesion-dependent cell spreading GO:1900025 ISO
    regulation of ruffle assembly GO:1900027 ISO
    negative regulation of protein phosphorylation GO:0001933 ISO
    negative regulation of focal adhesion assembly GO:0051895 ISO
    neural crest cell migration GO:0001755 ISO
    regulation of epithelial cell migration GO:0010632 ISO
    activation of GTPase activity GO:0090630 ISO
    establishment of protein localization GO:0045184 ISO
    actin cytoskeleton organization GO:0030036 IBA
    regulation of focal adhesion assembly GO:0051893 ISO
Subcellular Localization
    flotillin complex GO:0016600 ISO
    focal adhesion GO:0005925 ISO
    cytoskeleton GO:0005856 ISO
    actin cytoskeleton GO:0015629 ISO
    lateral plasma membrane GO:0016328 ISO
    vesicle GO:0031982 ISO
    lamellipodium GO:0030027 ISO
 Experiment description of studies that identified Coro1c in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Coro1c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Coro1c is involved
No pathways found





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